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At temperatures above 70°C, all the bands except those from the β-turn (1668 and 1674 cm^sup -1^) possessed similar melting curves, which indicated that a major conformational change occurred in this temperature range caution celebrex dictionary medical vioxx .
4 strongly supported the conclusion that pretransitional conformation changes occurred at temperatures where the enzyme retained high activity (see Fig caution celebrex dictionary medical vioxx .
We attempted, by docking of the EIN^sup sc^ and EIC^sup sc^ domains, to model the whole structure of EI^sup sc^ trying to keep the active-site histidine (in the EIN^sup sc^ domain) close to the PEP binding site (in the EIC^sup sc^ domain) caution celebrex dictionary medical vioxx .
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1, the osmotic pressure data indicate that the dominant interaction between the protein particles is repulsive caution celebrex dictionary medical vioxx .
It is however known that the infective species include assembled prion protein (PrP) oligomers in an aberrant folded state called PrP^sup SC^ caution celebrex dictionary medical vioxx .
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