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INTRODUCTION Aminoacylase, a family of metalloenzymes found in many mammalian tissues and in microorganisms, catalyzes the stereospecific hydrolysis of acylamino acids to yield the corresponding organic acid and amino acid (1-3)
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33 K/min (80 K/h) yields similar CD melting curves (not shown), with the apparent T^sub m^ = 84°C identical to that of intact disks
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Effect of dipalmitoyl phosphatidylcholine vesicle curvature on the reaction with human apolipoprotein A-I
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This is significant for the topomer search model: we might expect to find departures from the folding time/ contact order correlation when, despite sharing the same topology of fold, one protein in a pair has an important diffusional subspace stabilized whereas the other does not
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In addition to the changes directly related to the intermolecular contact, CD4 binding also induces conformational changes away from the binding interface that are crucial for the subsequent events of viral entry into the host cell
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We discuss the importance of the dissolving temperature in the results section
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