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. Since the MG conformation is more flexible than a fully folded polypeptide, this could lead to better packing at the dimer interface, leading to more stable dimers
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. The proposed torsions are used to compute new Cartesian coordinates for the molecule
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. Inasmuch as sequence-specific effects are present over five- to nine-residue stretches, it is conceivable that there are native-like local biases as well as default biases for conformations such as polyproline II (48)
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. With respect to tryptophan residues, five spectral classes of emission spectra have been identified which exhibit significantly different emission peak maxima
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. As a result, the specifically-docked conformation exchanges only slowly with extended conformations, resulting in a relatively narrow and symmetric peak and an absence of peak shifts in the FRET efficiency histogram
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