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DISCUSSIONMolten globule (MG) folding intermediates have been characterized for a number of proteins (for reviews, see Kuwajima, 1989; Ptitsyn, 1992, 1995) lipitor muscle weakness .
Deterministic pressure dissociation and unfolding of triose phosphate isomerase: persistent heterogeneity of a protein dimer lipitor muscle weakness .
It was difficult to distinguish in this research whether the pretransitional changes occurred in the catalytic domain or the dimerization domain of ACYI lipitor muscle weakness .
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The PTS involves a cascade of phosphoryl-transfer steps from phosphoenolpyruvate (PEP) via phosphointermediates of the general cytosolic non-sugar-specific phosphotransferases enzyme I (EI) and the histidine-phosphocarrier (HPr) to sugar-specific enzyme II permeases lipitor muscle weakness .
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As a consequence the corresponding emission spectra that were measured during unfolding appear completely different (Fig lipitor muscle weakness .
Cheong, unpublished), applications of localized MRS to the above-mentioned processes would make embryonic development accessible to noninvasive in vivo investigations lipitor muscle weakness .
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For this reason all cells were exposed to the DMEM/ITS+/TGF-[beta]1 medium initially until pellets were formed lipitor muscle weakness .
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