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. The energy needed to make an eyeball, which is basically a globule of protein that encapsulates some water, is probably much less than what is needed to make the plug of fat and bone that covers the same space in blind cave fish
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. The preceding discussion suggests that harshly denaturing (as opposed to mildly denaturing) conditions can be thought of as close mimics of "perfect", rather than just good, solvents (50)
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