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42 kcal mol^sup -1^) and hydrophobic contacts (ΔΔG = + 4
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, 1997; Sipe and Cohen, 2000; Jackson and Clarke, 2000; Serpell, 2000; Dobson, 2003; Rochet et al
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Each has advantages and drawbacks, but it is not clear whether each applies to a restricted subset of real cases, or whether all might have something to say about the folding of any one protein
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.Changes in the 90° light scattering observed during heating and cooling of the apoA-2:DMPC complexes correlate with the CD changes (Fig
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. The difference in configurational entropy between two molecular conformations a and b can be estimated as ΔS = k^sub B^/2 ln(detσ^sub a^/detσ^sub b^), where σ^sub a^ and σ^sub b^, are the covariance matrices of atomic positional fluctuations of the two conformers and k^sub B^ is Boltzmann's constant
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. The same is observed for the bridging sheet of gp120 (squares in Fig
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.Freely Diffusing Single Hairpin Ribozymes Provide Insights into the Role of Secondary Structure and Partially Folded States in RNA FoldingPljevaljcic, GoranABSTRACTSingle-molecule fluorescence resonance energy transfer studies of freely diffusing hairpin ribozymes with different combinations of helical junction and loop elements reveal striking differences in their folding behavior
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