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DCVJ has not to our knowledge been used before on an amyloid system but has been employed on microtubule polymerization (Haidekker et al prilosec otc .
Three probes-ANS, DCVJ, and ThT-show increased fluorescence throughout the aggregation reaction, whereas Bis-ANS shows fluorescence decay (Fig prilosec otc .
The standard buffer was 10 mM Na phosphate, 0 prilosec otc .
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In the case of helical proteins, candidates for the structure of the gutters are nonspecific contacts of the helices, and the angular, rather than translational, degrees of freedom describing their mutual configurations prilosec otc .
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